Genome Editing Core
part of the Genome Editing and Animal Models Facility (GEAM)
GEAM provides support for the generation of novel genome edited models and a full suite of other genome editing applications:
- Generation of mouse, rat, and porcine CRISPR models
- Efficient generation of genome edited, clonal cell lines
- Genome-wide CRISPR screening
- Expert support for custom genome editing applications
Some common services
Stage 1: Consultation with users’ ensures we understand your project needs
Stage 2: Careful design of your project and high-quality of custom reagents
Stage 3:
- a. We will edit the cell line of your choice
- b. We will work with the Animal Models group to make your mouse, rat, or pig model
Stage 4:
- a. For cells in stage 3a, we will use customizable, efficient delivery and our high-throughput robotics to generate and track your clones
- b. For animal models in stage 3b, the Animal Models core will use microinjection to reliably deliver material or electroporation for maximal editing efficiency and viability
Stage 5: We will stringently characterize your edited alleles using efficient sequencing methods
Stage 6: Your models will be delivered to for your research applications and can be cryogenically banked as well.